Overexpression of anti-apoptotic genes or loss of proapoptotic genes promotes tumorigenesis. The pro-apoptotic gene p53 is frequently mutated in cancers.

TLS Online TPP Program

#Id: 7950

#Unit 2. Cellular Organization

Prior to transfer to a nascent chain in the lumen of the  ER, the oligosaccharide precursor is assembled on amembrane- attached anchor called dolichol phosphate, a longchain polyisoprenoid lipid

TLS Online TPP Program

#Id: 595

#Unit 2. Cellular Organization

How cro cause lytic cycle- proteolytic cleavage of lambda repressor

 

TLS Online TPP Program

#Id: 2302

#Unit 3. Fundamental Processes

As RNA polymerase moves along the DNA template, it unwinds the duplex at the front of the bubble (the unwinding point), and the DNA automatically reforms the double helix at the back (the rewinding point). 

1. The length of the transcription bubble is 12 to 14 bp, but the length of the RNA–DNA hybrid within the bubble is only 8 to 9 bp. 

2. As the enzyme moves along the template, the DNA duplex reforms, and the RNA is displaced as a free polynucleotide chain. 

3. The last 14 ribonucleotides in the growing RNA are complexed with the DNA and/or the enzyme at any given moment.

TLS Online TPP Program

#Id: 3805

#Unit 5. Developmental Biology

High PSF to food ratio is upregulate the translation of the PKA catalytic subunit PKA-C.

TLS Online TPP Program

#Id: 544

#Unit 2. Cellular Organization

Capsules often protect pathogenic bacteria from phagocytosis by the host cells.