Binding of Axin to the phosphorylated LRP protein and to Dishevelled disrupts the Axin–APC–CK1–GSK3–β-catenin complex. 

TLS Online TPP Program

#Id: 3205

#Unit 3. Fundamental Processes

.All these systems are prone to introducing errors during the repair process. 

TLS Online TPP Program

#Id: 3206

#Unit 3. Fundamental Processes

Photoreactivation is a nonmutagenic repair system that acts specifically on pyrimidine dimers

TLS Online TPP Program

#Id: 3207

#Unit 3. Fundamental Processes

Deamination of cytosine creates a U-G base pair. Uracil is preferentially removed from the mismatched pair

TLS Online TPP Program

#Id: 3215

#Unit 3. Fundamental Processes

Ultraviolet irradiation causes dimer formation between adjacent thymines. The dimer blocks replication and transcription. 

TLS Online TPP Program

#Id: 3217

#Unit 3. Fundamental Processes

The Uvr system makes incisions -12 bases apart on both sides of damaged DNA, removes the DNA between them, and resynthesizes new DNA.

TLS Online TPP Program

#Id: 3219

#Unit 3. Fundamental Processes

Transcribed genes are preferentially repaired when DNA damage occurs.