Primitive Groove

A depression that forms within the primitive streak that serves as an opening through which migrating cells pass into the deep layers of the embryo.

TLS Online TPP Program

#Id: 3346

#Unit 3. Fundamental Processes

Pol h (but not other translesion polymerases) correctly inserts As across from a thymine dimer, the use of other translesion polymerases may increase the frequency of mutagenesis

TLS Online TPP Program

#Id: 3348

#Unit 3. Fundamental Processes

Direct repair of alkylated bases by AlkB

TLS Online TPP Program

#Id: 3349

#Unit 3. Fundamental Processes

The AlkB protein is an alpa-ketoglutarate-Fe2+ dependent hydroxylase. It catalyzes the oxidative demethylation of 1-methyladenine and 3-methylcytosine residues

TLS Online TPP Program

#Id: 3350

#Unit 3. Fundamental Processes

Methyltransferase catalyzes the transfer of the methyl group on O6 -methylguanine to a cysteine residue on the enzyme, thereby restoring the normal G in DNA.

TLS Online TPP Program

#Id: 3352

#Unit 3. Fundamental Processes

Photoreactivation directly reverses the formation of pyrimidine dimers that result from ultraviolet irradiation.

TLS Online TPP Program

#Id: 3354

#Unit 3. Fundamental Processes

In photoreactivation, the enzyme DNA photolyase captures energy from light and uses it to break the covalent bonds linking adjacent pyrimidines.