Live, Attenuated Vaccines Microorganisms can be attenuated or disabled so that they lose their ability to cause significant disease but retain their capacity for transient growth within an inoculated host.

TLS Online TPP Program

#Id: 8883

#Unit 2. Cellular Organization

Once mitotic CDKs are activated at the end of G2 , they phosphorylate specific serine residues in all 3 nuclear lamins.

TLS Online TPP Program

#Id: 8884

#Unit 2. Cellular Organization

This phosphorylation, together with phosphorylation of lamin B by protein kinase C, causes depolymerization of the lamin intermediate filaments.

TLS Online TPP Program

#Id: 8885

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8886

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8887

#Unit 2. Cellular Organization

The mitotic CDKs phosphorylate specific nucleoporins, which causes nuclear pore complexes to dissociate during prophase. 

TLS Online TPP Program

#Id: 8888

#Unit 2. Cellular Organization

A key function of mitotic CDKs, together with other protein kinases and ubiquitin-protein ligases, is to induce the formation of the mitotic spindle, also known as the mitotic apparatus.