Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α].

TLS Online TPP Program

#Id: 2098

#Unit 8. Inheritance Biology

Chromosome duplications are one way in which new genes evolve.

TLS Online TPP Program

#Id: 2099

#Unit 8. Inheritance Biology

Segmental duplications have played an important role in the evolution of human chromosomes; about 4% of the human genome consists of segmental duplications.

TLS Online TPP Program

#Id: 2100

#Unit 8. Inheritance Biology

Unbalanced gene dosage leads to developmental abnormalities.

TLS Online TPP Program

#Id: 2101

#Unit 8. Inheritance Biology

Chromosome deletion- Loss of a chromosome segment.

TLS Online TPP Program

#Id: 2102

#Unit 8. Inheritance Biology

Deletion include,

a. Terminal deletion

b. Intercalary/interstitial deletion 

c. Microdeletion

TLS Online TPP Program

#Id: 2103

#Unit 8. Inheritance Biology

Cri-du-chat syndrome- Deletion on 5, short arm