Increase in intracellular cAMP facilitates the opening of L channels, increasing ICa and the rapidity of the depolarization phase of the impulse.

TLS Online TPP Program

#Id: 1735

#Unit 4. Cell Communication and Cell Signaling

Diagnostic approach

1. Skin testing

2. Measure the serum levels of either total or allergen specific IgE using ELISA or Western blot technologies

TLS Online TPP Program

#Id: 1736

#Unit 4. Cell Communication and Cell Signaling

Antigen pieces are held within the binding groove of a cell surface protein called the major histocompatibility complex (MHC) molecule which recognized by T cell

TLS Online TPP Program

#Id: 1737

#Unit 4. Cell Communication and Cell Signaling

Class I MHC, glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I is presentation of endogenous peptide antigens to CD8+ T cells.

TLS Online TPP Program

#Id: 1738

#Unit 4. Cell Communication and Cell Signaling

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.

TLS Online TPP Program

#Id: 1739

#Unit 4. Cell Communication and Cell Signaling

Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α].

TLS Online TPP Program

#Id: 1740

#Unit 4. Cell Communication and Cell Signaling

Daudi tumor cells, which are unable to synthesize β 2-microglobulin.