MHC-Peptide Interaction

TLS Online TPP Program

#Id: 1215

#Unit 7. System Physiology – Animal

The role of parathyroid hormone is to regulate the concentration of Ca2+ in ECF.

TLS Online TPP Program

#Id: 1216

#Unit 7. System Physiology – Animal

The chief cells of the parathyroid glands synthesize and secrete PTH.

TLS Online TPP Program

#Id: 1217

#Unit 7. System Physiology – Animal

The parathyroid cell membrane contains Ca2+ sensing receptors that are linked, via a G protein (Gq).

TLS Online TPP Program

#Id: 1218

#Unit 7. System Physiology – Animal

When extracellular Ca2+ concentration is increased  Ca2+ binds to the receptor  activates phospholipase C inhibits PTH secretion.

TLS Online TPP Program

#Id: 1219

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion

TLS Online TPP Program

#Id: 1220

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion