TLS Online TPP Program

#Id: 2050


X-Linked Dominant Trait
a. Both males and females are usually affected; often, more females than males are affected.
b. Does not skip generations. Affected sons must have an affected mother; affected daughters must have either an affected mother or an affected father.
c. Affected fathers pass the trait to all their daughters.
d. Affected mothers (if heterozygous) pass the trait to half of their sons and half of their daughters.

#Unit 8. Inheritance Biology #Pedigree Analysis #Part B Pointers
More Pointers
TLS Online TPP Program

#Id: 7368

#Unit 5. Developmental Biology

The transition from specification to determination in Drosophila is mediated by Segmentation genes.


TLS Online TPP Program

#Id: 7369

#Unit 5. Developmental Biology

First zygotic genes is Gap genes. Mutations in them cause gaps in the segmentation pattern.


TLS Online TPP Program

#Id: 7370

#Unit 5. Developmental Biology

Gap genes encode transcription factors, and differing combinations and concentrations of gap gene proteins regulate the transcription of pair-rule genes, which divide the embryo into periodic units.


TLS Online TPP Program

#Id: 7371

#Unit 5. Developmental Biology

The transcription factors encoded by the pair-rule genes activate the segment polarity genes, whose mRNA and protein products divide the embryo into 14-segment-wide units, establishing the periodicity of the embryo. 


TLS Online TPP Program

#Id: 7372

#Unit 5. Developmental Biology

Major genes affecting segmentation pattern 

1.Gap genes                 2. Pair rule genes(primary)           3. Segment polarity genes      

Kruppel (Kr)                    hairy(h)                                             engrailed (en)

knirps (kni)                      even skipped(eve)                           wingless (wg)

hunchback (hb)              runt(run)                                           cubitus interruptus(ci) 

giant (gt)                          Pair rule genes (secondary)           hedgehog(hh)

tailless (til)                       fushi tarazu (ftz)                              fused (fu)

huckebein (hkb)              odd paired (opa)                             armadillo (arm)

buttonhead (btd)            odd skipped (odd)                          patched (ptc)

empty spiracles (ems)    sloppy paired (slp)                          gooseberry (gsb)

orthodenticle (otd)         paired (prd)                                      pangolin (pan

TLS Online TPP Program

#Id: 7373

#Unit 5. Developmental Biology

At the same time, the protein products of the gap, pair-rule, and segment polarity genes interact to regulate another class of genes, the homeotic selector genes, whose transcription determines the developmental fate of each segment