Leber hereditary optic neuropathy (LHON)- People who have this disorder experience rapid loss of vision in both eyes, which results from the death of cells in the optic nerve.

TLS Online TPP Program

#Id: 10332

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10333

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10334

#Unit 4. Cell Communication and Cell Signaling

B cell is type of lymphocyte.

B cell synthesized and maturation in bone marrow.

TLS Online TPP Program

#Id: 10335

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10336

#Unit 4. Cell Communication and Cell Signaling

They are pAPCs

Have surface marker  CD19

Antibodies at surface of b cell – IgM, IgD

Cause humoral immunity or antibodies mediated immunity

TLS Online TPP Program

#Id: 10337

#Unit 4. Cell Communication and Cell Signaling

Surface protein on B cell

CR2(CR21)

CD19

TAPA-1(CD81)

mIg 

Igα/ Igβ

(CD79a and CD79B)

TLR

CD40

B7(CD80/86)

ICAM-1

MHC-1 and 2 both

CD 22