In E. coli, rRNA synthesis from the seven rRNA operons responds to cellular growth rate and to changes in the availability of crucial nutrients, particularly amino acids. The regulation coordinated with amino acid concentrations is known as the stringent response.

TLS Online TPP Program

#Id: 8945

#Unit 2. Cellular Organization

Tem1-GTP activates a protein kinase cascade, which promotes the release of active Cdc14 from the nucleolus and exit from mitosis. 

TLS Online TPP Program

#Id: 8946

#Unit 2. Cellular Organization

An inhibitor of the GTPase, called Kin4, localizes to the parent cell but is absent from the bud.

TLS Online TPP Program

#Id: 8947

#Unit 2. Cellular Organization

An inhibitor of Kin4, called Lte1, localizes to the bud but is absent from the parent cell; it inhibits any residual Kin4 that leaks into the bud.

TLS Online TPP Program

#Id: 8948

#Unit 2. Cellular Organization

When spindle microtubule elongation at the end of anaphase has correctly positioned segregating daughter chromosomes in the bud, Tem1 is converted into its active GTP-bound state, activating the protein kinase signaling cascade.

TLS Online TPP Program

#Id: 8949

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 629

#Unit 3. Fundamental Processes

Replacement of Purine to Purine is called Transition