Slab gels can develop a “Smiling Effect” When in a gel more Joule heat is produced than can be dissipated, leads to the higher mobility of the ions in the center, resulting in an uneven distribution of the zones, These zones bend up at the two lateral sides, causing “smiling.” 

TLS Online TPP Program

#Id: 10433

#Unit 4. Cell Communication and Cell Signaling

Carcinogens can be classified into two categories: 

1. Direct-acting carcinogens

2. Indirect-acting carcinogens

TLS Online TPP Program

#Id: 1435

#Unit 4. Cell Communication and Cell Signaling

Four types of anchoring junctions are present in cells:

1. Adherens junctions

2. Desmosomes

3. Hemidesmosomes

4. Focal adhesions

TLS Online TPP Program

#Id: 529

#Unit 2. Cellular Organization

Sequences that presumably diverged as a result of gene duplication are paralogous.

TLS Online TPP Program

#Id: 10567

#Unit 4. Cell Communication and Cell Signaling

Inflammation due to necroptosis has been implicated in mediating major human inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease,

amyotrophic lateral sclerosis, Alzheimer’s disease and progressive atherosclerotic lesions

TLS Online TPP Program

#Id: 3209

#Unit 4. Cell Communication and Cell Signaling

Dominant gain-of-function mutations in proto-oncogenes and recessive loss-of-function mutations in tumor-suppressor genes are oncogenic.