Nurturing Life Sciences
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#Unit 2. Cellular Organization
Core DNA has an invariant length of 146 bp, the minimum length of DNA needed to form a stable monomeric nucleosome, and is relatively resistant to digestion by nucleases- DNA FINGER PRINTING
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The predicted mass of the nucleosome is 262 kD.
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The nucleosome consists of approximately equal masses of DNA and histones (including H1).
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H32-H42 tetramer accounts for the diameter of the octamer. It forms the shape of a horseshoe.
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All four core histones show a similar type of structure in which three a-helices are connected by two loops. This highly conserved structure is called the histone fold.