Nuclear run-on transcription is a way of ascertaining which genes are active in a given cell by allowing transcription of these genes to continue in isolated nuclei.

TLS Online TPP Program

#Id: 3622

#Unit 3. Fundamental Processes

Mutations that remove the 2'-OH of the A residue at the 3' end of the P-site tRNA result in a 10⁶ -fold reduction in catalysis rates.

TLS Online TPP Program

#Id: 3627

#Unit 3. Fundamental Processes

Mitochondria have their own tRNAs, so their code variations do not affectthe much larger cellular genome.

TLS Online TPP Program

#Id: 3628

#Unit 3. Fundamental Processes

The genetic code, in effect, is defined by two elements:

(1) the anticodons on tRNAs

(2) the specificity of the enzymes.

TLS Online TPP Program

#Id: 3629

#Unit 3. Fundamental Processes

When several codons encode the same amino acid and utilize multiple tRNAs, not all of the codons are used with equal frequency. In a phenomenon called codon bias.

TLS Online TPP Program

#Id: 3630

#Unit 3. Fundamental Processes

Transfer RNAs base-pair with mRNA codons at a three-base sequence on the tRNA called the anticodon.

TLS Online TPP Program

#Id: 3631

#Unit 3. Fundamental Processes

Wobble Allows Some tRNAs to Recognize More than One Codon.