General structure and component of a chromatographic system

A stationary phase – typically an aqueous buffer with sufficient ionic strength to maintain a soluble protein.

A column -

An injector system: To deliver test samples to the top of the column in a reproducible manner.

A detector with data acquisition - To give a continuous record of the presence of the analytes in the eluate as it emerges from the column.

A fraction collector: For collecting the separated analytes for further biochemical studies.

TLS Online TPP Program

#Id: 5812

#Unit 7. System Physiology – Animal

Zona glomerulosa cells capable of secreting significant amounts of aldosterone because they contain the enzyme aldosterone synthase

TLS Online TPP Program

#Id: 5813

#Unit 7. System Physiology – Animal

Zona glomerulosa lacks 17α-hydroxylase

Increases Na+ reabsorption Increases K+ secretion Increases H+ secretion

TLS Online TPP Program

#Id: 5814

#Unit 7. System Physiology – Animal

The synthesis and secretion of steroid hormones by the adrenal cortex depend on the stimulation of cholesterol desmolase by ACTH

TLS Online TPP Program

#Id: 5815

#Unit 7. System Physiology – Animal

The zona fasciculata/reticularis, is under the exclusive control of the hypothalamic-pituitary axis.

TLS Online TPP Program

#Id: 5816

#Unit 7. System Physiology – Animal

Negative feedback  is exerted by cortisol in the hypothalamic- pituitary axis.

TLS Online TPP Program

#Id: 5817

#Unit 7. System Physiology – Animal

The zona glomerulosa is controlled via; Renin-angiotensin- aldosterone system