As the origins are hemimethylated they bind to the cell membrane and may be unavailable to methylases. 

TLS Online TPP Program

#Id: 6461

#Unit 3. Fundamental Processes

A significant difference between the transcription of eukaryotic and prokaryotic RNAs is that in bacteria, transcription takes place on  RNA polymerase III synthesizes small RNAs in the nucleoplasm

TLS Online TPP Program

#Id: 6462

#Unit 3. Fundamental Processes

A typical gene transcribed by RNA polymerase II has a promoter that extends upstream from the site where transcription is initiated.

TLS Online TPP Program

#Id: 6463

#Unit 3. Fundamental Processes

A regulatory site that binds more negative regulators than positive regulators to control transcription is called a silencer.

TLS Online TPP Program

#Id: 6464

#Unit 3. Fundamental Processes

Promoters that are constitutively expressed and needed in all cells (their genes are sometimes called housekeeping genes) have upstream sequence elements that are recognized by ubiquitous activators.

TLS Online TPP Program

#Id: 6465

#Unit 3. Fundamental Processes

Proteins bound at enhancer elements interact with proteins bound at promoter elements via DNA looping, very often through intermediates called coactivators.

TLS Online TPP Program

#Id: 6466

#Unit 3. Fundamental Processes

Eukaryotic transcription is most often under positive regulation: A transcription factor is provided under tissue-specific control to activate a promoter or set of promoters that contain a common target sequence.