ORC was first found in S. cerevisiae (where it may be called scORC),but similar complexes have now been characterized in Schizosaccharomyces pombe (spORC), Drosophila (DmORC ), and Xenopus (XIORC).

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#Id: 2626

#Unit 13. Methods in Biology

Steps of nick translation- 

Low concentrations of DNase I are used to make occasional single-strand nicks in the double-stranded DNA that is intended as the gene probe.

DNA polymerase then fills in the nicks, using an appropriate dNTP, at the same time making a new nick to the 3′ side of the previous one.

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#Id: 2867

#Unit 13. Methods in Biology

Cystine (Cys2) possesses a weak absorption maximum of similar strength as phenylalanine at 250 nm.

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#Id: 10371

#Unit 4. Cell Communication and Cell Signaling

A given MHC molecule can bind numerous different peptides, and some peptides can bind to several different MHC molecules. Because of this MHC molecule is often referred to as “promiscuous”.

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#Id: 7503

#Unit 4. Cell Communication and Cell Signaling

RAG1 is expressed at all phases of the cell cycle, RAG2 is stable only in G0- or G1-phase cells.

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#Id: 87

#Unit 5. Developmental Biology

Cell Specification

cells become specified to a specific fate