Nurturing Life Sciences
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The key event in controlling replication is the behavior of the ORC complex at the origin.
Cdc6 protein is an unstable protein that is synthesized only in G1.
Cdc6 binds to ORC and allows MCM proteins.
Cdc6 binds to ORC and allows MCM proteins to bind.
Cdt1 facilitates MCM loading on origins
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#Unit 11. Evolution and Behavior
Where, though, do these hereditary variations come from? This was the great gap in Darwin’s theory, and he never filled it.
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Orthogenesis - “Straight-line evolution,” held that the variation that arises is directed toward fixed goals.
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Mutationist - Theories were advanced by some geneticists who observed that discretely different new phenotypes can arise by a process of mutation.
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Ronald A. Fisher, John B. S. Haldane and Sewall Wright- which showed that mutation and natural selection together cause adaptive evolution.
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Theory of recapitulation - Ernst Haeckel