The coupled 5'-3' synthetic/ 3'-5' exonucleolytic action is used most extensively for filling in short single-stranded regions in double-stranded DNA. These regions arise during lagging strand DNA replication.

TLS Online TPP Program

#Id: 713

#Unit 3. Fundamental Processes

Physical sequestration of the origin, delay in remethylation, competition for DnaA binding, hydrolysis of DnaA- bound ATP, and repression of dnaA transcription are the key steps to regulate initiation.

TLS Online TPP Program

#Id: 714

#Unit 3. Fundamental Processes

The entire genome must be replicated precisely, once for every cell division.

TLS Online TPP Program

#Id: 715

#Unit 3. Fundamental Processes

Once replication has started, it continues until the entire genome has been duplicated.

TLS Online TPP Program

#Id: 716

#Unit 3. Fundamental Processes

The unit of DNA in which an individual act of replication occurs is called the replicon

TLS Online TPP Program

#Id: 717

#Unit 3. Fundamental Processes

“Replicon” is usually applied to eukaryotic chromosomes to describe a unit of replication that contains an origin; trans-acting regulator protein

TLS Online TPP Program

#Id: 718

#Unit 3. Fundamental Processes

A replicon has origin at which replication is initiated. It may also have a terminus at which replication stops.