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The oxoG adduct is highly mutagenic because it can base-pair with adenine as well as with cytosine. If it base-pairs with adenine during replication, it gives rise to a G:C to T:A transversion, which is one of the most common mutations found in human cancers.





#Unit 3. Fundamental Processes #Mutation and Repair #Part B Pointers
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#Id: 963

#Unit 5. Developmental Biology

The point of sperm entry -determines dorsal-ventral axis

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#Id: 3656

#Unit 3. Fundamental Processes

Certain proteins, such as the enzymes glutathione peroxidase and formate dehydrogenase, contain an unusual amino acid called selenocysteine, which is part of the catalytic center of the enzymes.

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#Id: 8281

#Unit 1. Molecules and their Interaction Relevant to Biology

In absence of water the magnitude of the charge–charge interaction is significantly greater.

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#Id: 5798

#Unit 7. System Physiology – Animal

The thyroid hormone receptor usually forms a heterodimer with retinoid X receptor (RXR) at specific thyroid hormone response elements on the DNA


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#Id: 1484

#Unit 4. Cell Communication and Cell Signaling

Monomers and dimers of p53, exists in the cytoplasm. 

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