All DNA polymerases require a 3'-0H priming end to initiate DNA synthesis.

TLS Online TPP Program

#Id: 3112

#Unit 3. Fundamental Processes

A replication bubble forms a θ structure in circular DNA.

TLS Online TPP Program

#Id: 3114

#Unit 3. Fundamental Processes

Bacterial replicons are usually circles that replicate bidirectionally from a single origin.

TLS Online TPP Program

#Id: 3115

#Unit 3. Fundamental Processes

The origin of E. coli, oriC, is 245 bp in length.

TLS Online TPP Program

#Id: 3117

#Unit 3. Fundamental Processes

The origin of E. coli, oriC, is 245 bp in length. The genome of E. coli is replicated bidirectionally from a single unique site called the origin, identified as the genetic locus oriC.

Two replication forks initiate atoriCand move around the genome at approximately the same speed to a special termination region.

TLS Online TPP Program

#Id: 3118

#Unit 3. Fundamental Processes

A replication fork moves 10X faster than RNA polymerase. 

TLS Online TPP Program

#Id: 3120

#Unit 3. Fundamental Processes

oriC contains binding sites for DnaA: dnaA-boxes.