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TLS Online TPP Program

#Id: 3161

The conserved function of the replication components extends to the clamp loader and processivity clamp as well other functions of the replisome.

The roles of RFC and PCNA are analogous to the E. coli γ clamp loader and β2 processivity unit


#Unit 3. Fundamental Processes #Unit of replication and enzymes involved #Part B Pointers
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TLS Online TPP Program

#Id: 8652

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8653

#Unit 2. Cellular Organization

Degradation of Sic1 is induced by its phosphorylation by G1/S phase CDKs.
TLS Online TPP Program

#Id: 8654

#Unit 2. Cellular Organization

Sic1 inhibitor is degraded following its ubiquitinylation by the SCF ubiquitin-protein ligase
TLS Online TPP Program

#Id: 8655

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8656

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8846

#Unit 2. Cellular Organization

In budding yeast CKI p27 = Sic1 in metazoans