Mutations in three broad classes of genes play key roles in cancer induction: 

Proto-oncogenes genes
Tumor-suppressor genes
Genome maintenance genes

TLS Online TPP Program

#Id: 1433

#Unit 4. Cell Communication and Cell Signaling

Integrins have an important function in neuroregeneration after injury of the peripheral nervous system.

TLS Online TPP Program

#Id: 1434

#Unit 4. Cell Communication and Cell Signaling

Three major classes of animal-cell junctions: 

1. Anchoring junctions

2. Tight junctions

3. Gap junctions

TLS Online TPP Program

#Id: 1435

#Unit 4. Cell Communication and Cell Signaling

Four types of anchoring junctions are present in cells:

1. Adherens junctions

2. Desmosomes

3. Hemidesmosomes

4. Focal adhesions

TLS Online TPP Program

#Id: 1436

#Unit 4. Cell Communication and Cell Signaling

Adherens junctions 

Adhesion type- Cell-cell

Principal CAMs- Cadherins

Cytoskeletal attachment- Actin filaments

TLS Online TPP Program

#Id: 1437

#Unit 4. Cell Communication and Cell Signaling

Adherens junctions  functions as a tension cable that can internally brace the cell and thereby control its shape.

TLS Online TPP Program

#Id: 1438

#Unit 4. Cell Communication and Cell Signaling

Desmosomes

Adhesion type- Cell-cell

Cytoskeletal attachment- Intermediate filaments