Mismatches between the strands of DNA are one of the major targets for excision repair systems. Mismatch repair (MMR) is accomplished by scrutinizing DNA for apposed bases that do not pair properly

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#Unit 2. Cellular Organization

The second parity rule applies more closely to introns than to exons.

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#Unit 2. Cellular Organization

The length of Introns is variable while exons are almost constant in length.

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#Unit 2. Cellular Organization

Genes that share a common ancestry have similar organizations with conservation of the positions (of at least some) of the introns.

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#Unit 2. Cellular Organization

The homology between two genes can be plotted in the form of a dot matrix comparison

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#Unit 2. Cellular Organization

Sequences that presumably diverged as a result of gene duplication are paralogous.

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#Unit 2. Cellular Organization

A gene family is defined as a group of genes that encode related or identical products as a result of gene-duplication events.