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TLS Online TPP Program

#Id: 3257

Intercalating agents, such as proflavin, acridine, and ethidium, cause the deletion or addition of a base pair or even a few base pairs.

#Unit 3. Fundamental Processes #DNA damage and repair mechanisms #Part B Pointers
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TLS Online TPP Program

#Id: 1772

#Unit 4. Cell Communication and Cell Signaling

CTLA-4 bind to CD80/86 and inhibits T-cell.
TLS Online TPP Program

#Id: 1773

#Unit 4. Cell Communication and Cell Signaling

Third mechanism for maintaining tolerance, in addition to T-cell anergy and apoptosis, is through the activity of regulatory T cells (TREG cells).
TLS Online TPP Program

#Id: 1774

#Unit 4. Cell Communication and Cell Signaling

TREG can be generated both naturally, in the thymus (nTREG cells), and after induction by antigen in the periphery (iTREG cells).
TLS Online TPP Program

#Id: 1775

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 1776

#Unit 4. Cell Communication and Cell Signaling

In the presence of antigen and TGF-β, CD8+ regulatory T cells expressing FoxP3 can be induced (iTREG).
TLS Online TPP Program

#Id: 1777

#Unit 4. Cell Communication and Cell Signaling

Three main pathways of CD8+ regulatory T cells:
a. APC lysis
b. Inhibition of APC function
c. Regulation of effector T cells