Nicking is followed by the action of a specific helicase (UvrD) and one of three exonucleases.

TLS Online TPP Program

#Id: 6553

#Unit 7. System Physiology – Animal

TLS Online TPP Program

#Id: 6554

#Unit 7. System Physiology – Animal

Type 1 diabetes (insulin-dependent diabetes mellitus) ] is due to insulin deficiency caused by autoimmune destruction of the B cells in the pancreatic islets

TLS Online TPP Program

#Id: 6555

#Unit 7. System Physiology – Animal

Type 2 diabetes (non-insulin-dependent diabetes mellitus) is characterized by the dysregulation of insulin release from the B cells, along with insulin resistance in peripheral tissues such as skeletal muscle, brain, and liver

TLS Online TPP Program

#Id: 6556

#Unit 7. System Physiology – Animal

Glucagon Secretion is increased by hypoglycaemia and decreased by a rise in plasma glucose

TLS Online TPP Program

#Id: 6557

#Unit 7. System Physiology – Animal

Human preproglucagon is a 179-amino-acid protein that is found in pancreatic A cells, in L cells in the lower GIT, and in the brain

TLS Online TPP Program

#Id: 6558

#Unit 7. System Physiology – Animal

In A cells, preproglucagon is processed primarily to glucagon and major proglucagon fragment (MPGF)