Some prokaryotic ORFs lack a strong RBS but are nonetheless actively translated Using the phenomenon of translational coupling.

TLS Online TPP Program

#Id: 7900

#Unit 2. Cellular Organization

Leber’s hereditary optic neuropathy

caused by a missense mutation in the mtDNA gene

encoding subunit 4 of the NADH-CoQ reductase

TLS Online TPP Program

#Id: 9935

#Unit 4. Cell Communication and Cell Signaling

In staphylococcal food poisoning and toxic shock syndrome, exotoxins produced by the pathogens function as superantigens, which can activate all T cells. 

TLS Online TPP Program

#Id: 659

#Unit 3. Fundamental Processes

Telomeric sequence is the extension of the G-T–rich strand, which for 14 to 16 bases is usually a single strand.

TLS Online TPP Program

#Id: 7084

#Unit 3. Fundamental Processes

Mutations that remove the 2’-OH of the A residue at the 30 end of the P-site tRNA result in a 106-fold reduction in catalysis rates. This “substrate-assisted catalysis”

2’-OH of the P-site tRNA may act as part of a “proton shuttle”

TLS Online TPP Program

#Id: 2426

#Unit 3. Fundamental Processes

Initiation relies solely upon the interaction between RNA polymerase and duplex DNA, however, the termination event also involves recognition of signals in the transcript by RNA polymerase.