Different thalassemias are caused by various deletions that eliminate a- or b-globin genes. The severity of the disease depends on the individual deletion.

TLS Online TPP Program

#Id: 2175

#Unit 11. Evolution and Behavior

Selection coefficients-  The allelic frequency at equilibrium (qˆ) depends on the relative fitnesses of the two homozygotes:

TLS Online TPP Program

#Id: 2176

#Unit 11. Evolution and Behavior

Positive Selection: The Spread of Beneficial Mutations

TLS Online TPP Program

#Id: 2177

#Unit 11. Evolution and Behavior

Hitchhiking - An allele at one locus spreads by natural selection acting on a second locus that is in linkage disequilibrium with  the first.

TLS Online TPP Program

#Id: 2178

#Unit 11. Evolution and Behavior

Mutation and natural selection act as opposing forces on detrimental alleles.

TLS Online TPP Program

#Id: 2179

#Unit 11. Evolution and Behavior

Genetic drift and directional selection will eventually result in fixation of allele.

TLS Online TPP Program

#Id: 2180

#Unit 11. Evolution and Behavior

Natural selection increases or decrease divergence among populations.