Hb anti-Lepore, Hb Kenya result from unequal crossing over between linked genes

TLS Online TPP Program

#Id: 8524

#Unit 2. Cellular Organization

Detyrosylation 

tyrosine can be removed by a carboxypeptidase, where it sequentially removes the C-terminal tyrosines from α-tubulin subunits. 

TLS Online TPP Program

#Id: 8525

#Unit 2. Cellular Organization

Detyrosylated microtubules are more stable, because they are more resistant to depolymerization by kinesin-13 and related proteins.

TLS Online TPP Program

#Id: 8526

#Unit 2. Cellular Organization

Polyglutamylation and polyglycylation are likely mutually exclusive, so they would not normally occur at the same time & both can enhance microtubule stability,

TLS Online TPP Program

#Id: 8527

#Unit 2. Cellular Organization

Kinesin-1 associates preferentially with detyrosylated and acetylated microtubules.

TLS Online TPP Program

#Id: 8528

#Unit 2. Cellular Organization

Polyglutamylation has a key role in the beating of cilia and flagella

TLS Online TPP Program

#Id: 8529

#Unit 2. Cellular Organization

Class IV IF proteins compose the neurofilaments found in neurons.