Active genes are often found at the borders of chromosome territories, and active genes from several chromosomes may cluster in inter-chromosomal territories that are enriched in transcription machinery.

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#Unit 4. Cell Communication and Cell Signaling

Microbial Complement Evasion strategies

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#Unit 4. Cell Communication and Cell Signaling

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#Unit 4. Cell Communication and Cell Signaling

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#Unit 4. Cell Communication and Cell Signaling

The two β pleated sheets in each domain are held together by hydrophobic interactions and the conserved disulfide bond.  The three loops of each variable domain show considerable variation in length and amino acid sequence; these hyper variable regions  make up the antigen-binding site. 

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Hyper variable regions are usually called complementarity determining regions (CDRs).

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#Unit 4. Cell Communication and Cell Signaling

Classes of Antibody Heavy Chains