The nucleosome is of 10nm/100A diameter, compacting the DNA about 6-fold over the length of naked DNA. Its first level of organization. 200X3.4A=680A

TLS Online TPP Program

#Id: 2344

#Unit 3. Fundamental Processes

consensus sequence of TATAAT in which the leading TA and the final T are highly conserved. Upstream sequences around position –35 also have a region of sequence similarity, TTGACA. 

TLS Online TPP Program

#Id: 2345

#Unit 3. Fundamental Processes

Core enzyme binds indiscriminately to any DNA. Sigma factor reduces the affinity for sequence independent binding and confers specificity for promoter.

TLS Online TPP Program

#Id: 2346

#Unit 3. Fundamental Processes

Sigma factor reduces the affinity for sequence independent binding and confers specificity for promoter.

TLS Online TPP Program

#Id: 2347

#Unit 3. Fundamental Processes

Sigma seems to stimulate both initiation and elongation.

TLS Online TPP Program

#Id: 2348

#Unit 3. Fundamental Processes

Transcription Is Initiated by RNA Polymerase without the Need for a Primer known as de novo synthesis 

TLS Online TPP Program

#Id: 2349

#Unit 3. Fundamental Processes

RNA polymerase starts most transcripts with an A, and that ribonucleotide binds the template nucleotide (T) with only two hydrogen bonds (as opposed to the three between C and G).