About 75% of the charged residues in proteins are members of ion pairs that are located mostly on the protein surface.

Despite the strong electrostatic attraction interactions contribute little to the stability of a native protein.

TLS Online TPP Program

#Id: 8050

#Unit 1. Structure and Function of Biomolecules

Certain side-chain conformations are energetically favourable, these side chain confirmations are called as Rotamers.

TLS Online TPP Program

#Id: 8051

#Unit 1. Structure and Function of Biomolecules

TLS Online TPP Program

#Id: 8052

#Unit 1. Structure and Function of Biomolecules

1. Glucogenic amino acids- which are degraded to pyruvate, α-ketoglutarate, succinyl-CoA, fumarate, or oxaloacetate and are therefore glucose precursors

2. Ketogenic amino acids- which are broken down to acetyl-CoA or acetoacetate and can thus be converted to fatty acids or ketone bodies

TLS Online TPP Program

#Id: 8053

#Unit 1. Structure and Function of Biomolecules

1. Alanine is can be mutated to

TLS Online TPP Program

#Id: 8054

#Unit 1. Structure and Function of Biomolecules

TLS Online TPP Program

#Id: 8055

#Unit 1. Structure and Function of Biomolecules