If the antibody preparation is polyclonal and has a range of affinities, Scatchard plot yields a curved line whose slope is constantly changing. The average affinity constant K0 can be calculated by determining the value of Ka when half of the binding sites are occupied (i.e., when r  1 in this example). In this graph, antiserum #3 has a higher affinity (K0  2.4  108) than antiserum #4 (K0  1.25  108)

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#Id: 10014

#Unit 4. Cell Communication and Cell Signaling

Transcription Factor

zinc-finger transcription factor Cubitis interruptus

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#Id: 8470

#Unit 1. Molecules and their Interaction Relevant to Biology

The two forms of poly(Pro)

all cis (I) or all trans (II) peptide bonds. 

poly(Pro) I as a right-handed helix with 3.3 residues per turn 

poly(Pro) II is a left-handed helix with 3 residues per turn.

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#Id: 5731

#Unit 10. Ecological Principles

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#Id: 5263

#Unit 7. System Physiology – Animal

Phase 0 (depolarization), fast sodium channels open. 

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#Id: 8116

#Unit 1. Molecules and their Interaction Relevant to Biology

Fingolimod—a Sphingosine-1-P Mimic Is an Oral Drug for Multiple Sclerosis