Scatchard plots are based on repeated equilibrium dialyses with a constant concentration of antibody and varying concentration of ligand. 

If all antibodies have the same affinity, then a Scatchard plot yields a straight line with a slope of Ka. The x intercept is n, the valency of the antibody, which is 2 for IgG and other divalent Igs. For IgM, which is pentameric, n  10, and for dimeric IgA, n  4. In this graph, antibody #1 has a higher affinity than antibody #2. .  

TLS Online TPP Program

#Id: 6338

#Unit 8. Inheritance Biology

ANDROGEN-INSENSITIVITY SYNDROME

These individuals have female external sexual characteristics. Vagina ends blindly and that the uterus, oviducts, and ovaries are absent.

 Inside the abdominal cavity, a pair of testes produce levels of testosterone normally seen in males. 

Woman with androgen-insensitivity syndrome contain an X and a Y chromosome. 

Testosterone bind to an androgen receptor. This receptor is defective in females with androgen-insensitivity syndrome.

The gene for the androgen receptor is located on the X chromosome

TLS Online TPP Program

#Id: 6339

#Unit 8. Inheritance Biology

Sex-Linked Characteristics Characteristic determined by a gene or genes on sex chromosomes.

TLS Online TPP Program

#Id: 6340

#Unit 8. Inheritance Biology

X-linked characteristic Characteristic determined by a gene or genes on the X chromosome.  Y-linked characteristic  Characteristic determined by a gene or genes on the Y chromosome. The locus for the blue pigment is found on chromosome 7, and those for the green and the red pigments lie close together on the X chromosome.

TLS Online TPP Program

#Id: 6341

#Unit 8. Inheritance Biology

X-Linked White Eyes in Drosophila

TLS Online TPP Program

#Id: 6342

#Unit 8. Inheritance Biology

Nondisjunction Failure of homologous chromosomes or sister chromatids to separate in meiosis or mitosis.

TLS Online TPP Program

#Id: 6343

#Unit 8. Inheritance Biology

X-Linked Color Blindness in Humans 

The human eye perceives color through light-sensing cone cells that line the retina.  Each cone cell contains one of three pigments capable of absorbing light of a particular wavelength: one absorbs blue light, a second absorbs red light, and a third absorbs green light.