The stem cell lineage always undergoes meridional ,division to produce

(1) An anterior founder cell (AB)

(2) A posterior cell (P1) that will continue the stem cell lineage.

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#Unit 2. Cellular Organization

The first myosin discovered

Myosin II, was isolated from skeletal muscle.

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#Unit 2. Cellular Organization

Three classes of myosins:

Myosin I

Myosin II

Myosin V

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#Unit 2. Cellular Organization

Myosin I

single head domain

Function- Membrane association, endocytosis

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#Unit 2. Cellular Organization

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction

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#Unit 2. Cellular Organization

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport

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#Unit 2. Cellular Organization

The length of the myosin II neck domain determines the rate of movement.