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TLS Online TPP Program

#Id: 4778

If the P2 cell is removed at the early 4-cell stage, the EMS cell will divide into two MS cells, and no endoderm will be produced.


#Unit 5. Developmental Biology #Vulva formation in Caenorhabditis elegans #Part B Pointers
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TLS Online TPP Program

#Id: 413

#Unit 2. Cellular Organization

H2AX is normally present in only 10%–15% of the nucleosomes in multicellular eukaryotes
TLS Online TPP Program

#Id: 414

#Unit 2. Cellular Organization

H2AX subtype is has a C-terminal tail that is distinct from the canonical H2A, characterized by a SQEL/Y motif at the end.
TLS Online TPP Program

#Id: 415

#Unit 2. Cellular Organization

SQEL/Y motif of H2AX is phosphorylated by ATM/ATR kinases, activated by DNA damage, is involved in DNA repair
TLS Online TPP Program

#Id: 416

#Unit 2. Cellular Organization

H2AX phosphorylated at the SQEL/Y motif is sometimes referred to as “gamma-H2AX,”
TLS Online TPP Program

#Id: 417

#Unit 2. Cellular Organization

Gamma-H2AX frequently functions in DSBR
TLS Online TPP Program

#Id: 418

#Unit 2. Cellular Organization

H2AZ variant has 60% sequence identity with canonical H2A and involved in gene activation, heterochromatin–euchromatin boundary formation, cell-cycle progression.