The level of significance is denoted by the Greek symbol α (alpha).

Therefore, the level of significance is defined as follows: 

TLS Online TPP Program

#Id: 6705

#Unit 3. Fundamental Processes

The snoRNAs are 60 to 300 nucleotides long. Many are encoded within the introns of other genes and cotranscribed with those genes. Each snoRNA includes a 10 to 21 nucleotide sequence that is perfectly complementary to some site on an rRNA.

TLS Online TPP Program

#Id: 6706

#Unit 3. Fundamental Processes

There are two classes of snoRNPs involved in rRNA processing in nucleolus.  The box H/ACA snoRNPs are involved in pseudouridylylation, and box C/D snoRNPs function in 2-O-methylations.

TLS Online TPP Program

#Id: 6707

#Unit 3. Fundamental Processes

Cajal bodies are centers of RNP-complex assembly for spliceosomal snRNPs and other RNPs

TLS Online TPP Program

#Id: 6708

#Unit 3. Fundamental Processes

Conversion of specific uridine residues to pseudouridine and the addition of methyl groups to the 2′-hydroxyl groups

of specific riboses, that are important for the proper assembly and function of snRNPs in pre-mRNA splicing. 

These modifications occur in Cajal bodies, where they are directed by a class of snoRNA-like guide RNA molecules called scaRNAs (small Cajal body–associated RNAs)

TLS Online TPP Program

#Id: 6709

#Unit 3. Fundamental Processes

Cajal bodies are sites of reassembly of the U4/U6/U5 tri-snRNP complex from the free U4, U5, and U6 snRNPs released during the removal of introns from mRNAs

TLS Online TPP Program

#Id: 6710

#Unit 3. Fundamental Processes

p53 tumor suppressor protein appears to be post-translationally modified by phosphorylation and acetylation in PML nuclear bodies