DnaA is an ATP-binding protein.

The first stage in initiation is binding of the DnaA-ATP protein complex to the fully methylated oriC sequence.

This takes place in association with the inner membrane. DnaA is in the active form only when bound to ATP.

DnaA has intrinsic ATPase activity that hydrolyzes ATP to ADP and thus inactivates itself when the initiation stage ends.

TLS Online TPP Program

#Id: 9014

#Unit 6. System Physiology – Plant

TLS Online TPP Program

#Id: 8637

#Unit 2. Cellular Organization

The G1 cyclin-CDK complex (Cln3-CDK in yeast) stimulates the formation of G1/S phase cyclin-CDKs, which initiate bud formation, centrosome duplication, and DNA replication.

TLS Online TPP Program

#Id: 7909

#Unit 2. Cellular Organization

Membrane contact sites (MCSs)

Mitochondria establish MCSs with many other organelles, including ER, lysosomes, peroxisomes, the plasma membrane, the Golgi, endosomes, and even lipid droplets.

TLS Online TPP Program

#Id: 7415

#Unit 5. Developmental Biology

The homologue of TGF-β in Drosophila is Dpp.

TLS Online TPP Program

#Id: 9378

#Unit 11. Evolution and Behavior

Learned behaviors - which are genetically hardwired and can be performed without any prior experience or training.