Nurturing Life Sciences
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#Unit 2. Cellular Organization
Introns evolve or accumulate mutations/changes much more rapidly than exons
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Intron do not face selective pressure to produce a polypeptide with a useful sequence hence highly variable.
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Exon sequences are conserved by the negative selection of individuals in which the sequences have changed
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Most intron mutations are expected to be selectively neutral except branch site, splicing junctions, and sequences influencing splicing
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A mutation that confers a more advantageous phenotype to an organism, relative to Individuals in the same population without the mutation, is positive selection of that organism.
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Mutations conferring antibiotic resistance in bacteria or venom-resistance of pray is example of positive selection of mutation in exons