The basilar membrane is relatively permeable to perilymph in the scala tympani, and tunnel of the organ of Corti and the bases of the hair cells are bathed in perilymph

TLS Online TPP Program

#Id: 933

#Unit 5. Developmental Biology

The niche employs a variety of mechanisms of cell-to-cell communication to regulate the quiescent, proliferative, and differentiative states of the resident stem cell.

TLS Online TPP Program

#Id: 934

#Unit 5. Developmental Biology

The shoot apical and root apical meristems provide a continuous source of totipotent stem cells for a plant to generate a majority of its aerial and ground tissues throughout life.

TLS Online TPP Program

#Id: 935

#Unit 5. Developmental Biology

When a multipotent stem cell divides asymmetrically, its maturing daughter cell often goes through a transition stage as a progenitor or transit-amplifying cell.

TLS Online TPP Program

#Id: 936

#Unit 5. Developmental Biology

Precursor cell (or simply precursors), is widely used to denote any ancestral cell type (either stem cell or progenitor cell) of a particular lineage.

TLS Online TPP Program

#Id: 937

#Unit 5. Developmental Biology

Inner cell mass (ICM) cells of the mouse blastocyst are maintained in a pluripotent state through E-cadherin interactions with trophectoderm cells that activate the Hippo kinase cascade and repress the function of Yap/Taz as transcriptional regulators of Cdx2.

TLS Online TPP Program

#Id: 938

#Unit 5. Developmental Biology

Induced pluripotent stem cell (iPSC) with the pluripotency of an embryonic stem cell. These genes were 

a. Sox2 and Oct4 (Oct3, Oct3/4, and Pou5f1) -which activated Nanog and other transcription factors that   established pluripotency and blocked differentiation

b. c-Myc which opened up chromatin and made the genes accessible to Sox2, Oct4, and Nanog

c. Klf4 -which prevents cell death