The lac operon has three paradoxes

1-If the operon is in a repressed state, how does the inducer enter the cell to start the process of induction

2- If the operon is in a repressed state, how Repressor is removed with allolactose 

3- How is allolactose synthesized in Repressed state Answer is Leaky Expression

TLS Online TPP Program

#Id: 711

#Unit 3. Fundamental Processes

DnaA has a weak intrinsic activity that converts the ATP to ADP, this is enhanced by a factor termed Hda.

TLS Online TPP Program

#Id: 712

#Unit 3. Fundamental Processes

Hda is recruited by DNA Polymerase in previous cycle and it acts to switch off DnaA, preventing a second round of replication.

TLS Online TPP Program

#Id: 713

#Unit 3. Fundamental Processes

Physical sequestration of the origin, delay in remethylation, competition for DnaA binding, hydrolysis of DnaA- bound ATP, and repression of dnaA transcription are the key steps to regulate initiation.

TLS Online TPP Program

#Id: 714

#Unit 3. Fundamental Processes

The entire genome must be replicated precisely, once for every cell division.

TLS Online TPP Program

#Id: 715

#Unit 3. Fundamental Processes

Once replication has started, it continues until the entire genome has been duplicated.

TLS Online TPP Program

#Id: 716

#Unit 3. Fundamental Processes

The unit of DNA in which an individual act of replication occurs is called the replicon