Once the ER signal sequence emerges from the ribosome, it is bound by a signal recognition particle (SRP)

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Suppression of recombination

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Translocation

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Translocation Movement of genetic material between nonhomologous chromosomes or within the same chromosome.

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#Unit 8. Inheritance Biology

Reciprocal translocation - Reciprocal exchange of segments between two nonhomologous chromosomes.  Nonreciprocal translocation - Movement of a chromosome segment to a nonhomologous chromosome or chromosomal region without any reciprocal exchange of segments.

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EFFECTS OF TRANSLOCATIONS New linkage relations may affect gene expression. The chromosome breaks that bring about translocations may take place within a gene and disrupt its function.

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Robertsonian translocation

The long arms of two acrocentric chromosomes become joined to a common centromere through a translocation, generating a metacentric chromosome with two long arms and another chromosome with two very short arms. The smaller chromosome is often lost because very small chromosomes do not have enough mass to segregate properly during mitosis and meiosis.