Semiconservative replication

DNA repair reaction

TLS Online TPP Program

#Id: 7497

#Unit 4. Cell Communication and Cell Signaling

Recombination between the D and a JH gene segment occur during pre-pro-B cell to the early pro-B-cell stage.

TLS Online TPP Program

#Id: 7498

#Unit 4. Cell Communication and Cell Signaling

Recombination between the VH and D-JH segments follows during the pro-B-cell stage.

TLS Online TPP Program

#Id: 7499

#Unit 4. Cell Communication and Cell Signaling

VpreB and λ5 (called a surrogate light chain), to form a pre-B-cell receptor.

TLS Online TPP Program

#Id: 7500

#Unit 4. Cell Communication and Cell Signaling

Light-chain recombination occurs at the small pre-B-cell stage of B-cell development.

TLS Online TPP Program

#Id: 7501

#Unit 4. Cell Communication and Cell Signaling

Site of DNA cleavage - Recombination Signal Sequence (RSS) 

TLS Online TPP Program

#Id: 7502

#Unit 4. Cell Communication and Cell Signaling

Recognition of Recombination Signal Sequence (RSS) by the RAG1/RAG2 enzyme complex.