In DNA polymerase, the nucleotide-binding pocket cannot accommodate a 2’-OH on the in-coming nucleotide. This space is occupied by two amino acids that make van der Waals contacts with the sugar ring. Changing these amino acids to other amino acids with 

TLS Online TPP Program

#Id: 5052

#Unit 3. Fundamental Processes

DnaA-ATP in an extended multimeric state promoted by the accessory protein DiaA, which stimulates cooperative binding of DnaA.

DnaA-ATP binds cooperatively to form a helical central core around which oriC DNA is wrapped.

TLS Online TPP Program

#Id: 6169

#Unit 12. Applied Biology

The commercial Bt–cotton available today contain genes from the isolate B-thuringiensis, ssp. that produces Cry I A(a), Cry I A(b), Cry I A(c), Cry IIA.

TLS Online TPP Program

#Id: 6320

#Unit 3. Fundamental Processes

Rho is a member of the family of hexameric ATP-dependent helicases. Each subunit has an RNA-binding domain and an ATP hydrolysis domain.

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#Id: 2268

#Unit 11. Evolution and Behavior

TLS Online TPP Program

#Id: 9173

#Unit 11. Evolution and Behavior