To replace the RNA primers with DNA, an enzyme called RNaseH recognizes and removes most of each RNA primer. This enzyme specifically degrades RNA that is base-paired with DNA. RNase H removes all of the RNA primer except the ribonucleotide directly linked to the DNA end.
This is because RNaseH can only cleave bonds between two ribonucleotides. The final ribonucleotide is removed by a 5’ exonuclease that degrades RNA or DNA from their 5’ ends.
#Unit 3. Fundamental Processes#Mechanism of DNA synthesis in Prokaryotes#Part B Pointers
Promotes accumulation of G1 cyclins (CycD)