Orc2-5 binds strongly; Orc6 binds weakly to ARS and has a nuclear localization signal that must be activated by the cyclin/ CDK kinase during the G1 to S transition.

TLS Online TPP Program

#Id: 2651

#Unit 7. System Physiology – Animal

In the Descending part of the thin segment 

About 20 percent of the filtered water is reabsorbed

TLS Online TPP Program

#Id: 2652

#Unit 7. System Physiology – Animal

The ascending limb, both the thin & the thick segments

is virtually impermeable to water, a characteristic that is important for concentrating the urine.

TLS Online TPP Program

#Id: 2653

#Unit 7. System Physiology – Animal

The thin segment of the ascending limb has a much lower reabsorptive capacity than does the thick segment.

TLS Online TPP Program

#Id: 2654

#Unit 7. System Physiology – Animal

Thick segment of the ascending limb of loop of Henle, has thick epithelial cells that have high metabolic activity and are capable of active reabsorption of sodium, chloride, and potassium

TLS Online TPP Program

#Id: 2655

#Unit 7. System Physiology – Animal

About 25 percent of the filtered loads of sodium, chloride, and potassium are reabsorbed in thick segment of the ascending limb of loop of Henle

TLS Online TPP Program

#Id: 2656

#Unit 7. System Physiology – Animal

An important component of solute reabsorption in the thick ascending limb is the sodium-potassium ATPase pump in the epithelial cell basolateral membranes.