Direct repeats can be displaced and misaligned with the template; palindromic sequences can form hairpins. These structures may change the number of repeats. The general importance of FEN1 is that it prevents flaps of DNA from generating structures that may cause deletions or duplications in the genome.

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#Unit 4. Cell Communication and Cell Signaling

The first myosin discovered

Myosin II, was isolated from skeletal muscle.

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#Unit 4. Cell Communication and Cell Signaling

Three classes of myosins:

Myosin I

Myosin II

Myosin V

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#Unit 4. Cell Communication and Cell Signaling

Myosin I

single head domain

Function- Membrane association, endocytosis

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#Unit 4. Cell Communication and Cell Signaling

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction 

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#Unit 4. Cell Communication and Cell Signaling

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport

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#Unit 4. Cell Communication and Cell Signaling

All Myosins move toward the (+) end of an actin filament except myosin VI.