Sundaland

The Sundaland was declared as a World Biosphere Reserve by the United Nations. This region is famous for its rich terrestrial and marine ecosystem. Sundaland is one of the biologically richest hotspots in India which comprises 25,000 species of vascular plants, of which 15,000 are found only in this region.

TLS Online TPP Program

#Id: 449

#Unit 2. Cellular Organization

H32-H42 tetramer accounts for the diameter of the octamer. It forms the shape of a horseshoe.

TLS Online TPP Program

#Id: 450

#Unit 2. Cellular Organization

All four core histones show a similar type of structure in which three a-helices are connected by two loops. This highly conserved structure is called the histone fold.

TLS Online TPP Program

#Id: 451

#Unit 2. Cellular Organization

Nucleosomes that contain linker H1 histones are referred to as chromatosomes.

TLS Online TPP Program

#Id: 452

#Unit 2. Cellular Organization

Lysine  in the histone tails are the most common targets of modification.

TLS Online TPP Program

#Id: 453

#Unit 2. Cellular Organization

Acetylation, methylation, ubiquitylation, and sumoylation all occur on the free epsilon amino group of lysine.

TLS Online TPP Program

#Id: 454

#Unit 2. Cellular Organization

Acetylation neutralizes the positive charge of lysine so disrupts DNA Histone interactions.