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TLS Online TPP Program

#Id: 6099

There are two kind of mutation 
1. Base substitution
2. Frameshift

#Unit 3. Fundamental Processes #Mutation and Repair #Part B Pointers
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TLS Online TPP Program

#Id: 5790

#Unit 7. System Physiology – Animal

Thyroglobulin is a glycoprotein contains 123 tyrosine residues, but only 4–8 of these are normally incorporated into thyroid hormones.
TLS Online TPP Program

#Id: 5791

#Unit 7. System Physiology – Animal

Oxidation of iodine is mediated by thyroid peroxidase, a membrane-bound enzyme found in the thyrocyte apical membrane.
TLS Online TPP Program

#Id: 5792

#Unit 7. System Physiology – Animal

When the peroxidase system is blocked or when it is hereditarily absent from the cells, the rate of formation of thyroid hormones falls to zero
TLS Online TPP Program

#Id: 5793

#Unit 7. System Physiology – Animal

“Organification” of Thyroglobulin- Iodination of tyrosine and formation of the thyroid hormones
TLS Online TPP Program

#Id: 5794

#Unit 7. System Physiology – Animal

Tyrosine is first iodized to monoiodotyrosine and then to diiodotyrosine. Then, more and more of the iodotyrosine residues become coupled with one another
TLS Online TPP Program

#Id: 5795

#Unit 7. System Physiology – Animal