There are two kind of mutation 

1. Base substitution

2. Frameshift

TLS Online TPP Program

#Id: 6967

#Unit 8. Inheritance Biology

Burkitt lymphoma Burkitt lymphoma possess a reciprocal translocation between chromosome 8 and chromosome 2, 14, or 22.  This translocation relocates a gene called c-MYC is next to a gene that encodes an immunoglobulin protein.

TLS Online TPP Program

#Id: 10482

#Unit 4. Cell Communication and Cell Signaling

p53

extremely unstable protein and generally does not accumulate to high enough levels to stimulate transcription under normal conditions

TLS Online TPP Program

#Id: 1746

#Unit 4. Cell Communication and Cell Signaling

IFN-  has been shown to induce expression of the class II transcriptional activator (CIITA).

TLS Online TPP Program

#Id: 9043

#Unit 4. Cell Communication and Cell Signaling

Switching mechanism of monomeric G proteins 

“On” state, switch I and switch II, are bound to the terminal γ phosphate of GTP with the backbone amide groups of conserved T & G.

TLS Online TPP Program

#Id: 9345

#Unit 4. Cell Communication and Cell Signaling

TGF-β activation

By cytoskeletal force transmitted by integrins