Nurturing Life Sciences
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#Unit 5. Developmental Biology
Fgf8 is the major active factor in the AER.
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Hox9 and Hox10 paralogues specify the stylopod
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Hox11 paralogues specify the zeugopod
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Hox12 and Hox13 paralogues specify the autopod.
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AER of the fin bud changes into an apical ectodermal fold that promotes fin ray development.