OC are constitutive because repressor protein is unable to bind; this allows RNA polymerase to have unrestrained access to the promoter.  The Oc mutations are cis-acting/cis dominant, because they affect only the contiguous set of structural genes.

TLS Online TPP Program

#Id: 6128

#Unit 3. Fundamental Processes

Glycosylase action is followed by the endonuclease APE1, which cleaves the polynucleotide chain on the 5’ side. This in turn attracts a replication complex including the DNA polymerase d/E and ancillary components, which performs a short synthesis reaction extending for two to 10 nucleotides. The displaced material is removed by the endonuclease FEN1.

TLS Online TPP Program

#Id: 7501

#Unit 4. Cell Communication and Cell Signaling

Site of DNA cleavage - Recombination Signal Sequence (RSS) 

TLS Online TPP Program

#Id: 7298

#Unit 6. System Physiology – Plant

PPDK-RP make PPDK active removing phosphates of catalytic his/threo residues using ADP as phosphoryl donor, rather than ATP, and the phosphorolytic dephosphorylation of the (PPDK)−Thr−O−P with formation of pyrophosphate, rather than the hydrolysis employed by most protein

phosphatases.

TLS Online TPP Program

#Id: 385

#Unit 2. Cellular Organization

H32-H42 tetramer accounts for the diameter of the octamer and H32-H42 tetramer alone can organize DNA in vitro into particles that display the properties of the core particle.

 

TLS Online TPP Program

#Id: 3172

#Unit 3. Fundamental Processes

Deletion of the ter sites does not, however, prevent normal replication cycles from occurring, although it does affect segregation of the daughter chromosomes.